Notre Dame Vs Usc Predictions 2025. Notre dame defensive coordinator al golden spoke to reporters tuesday about playing with physicality on defense, several key defensive backs, usc’s quarterback situation. Get our free college football betting pick for the usc vs notre dame matchup and gain an edge as a college football bettor.
Sp+ predicts that notre dame will defeat usc by a projected score of 32 to 21 and win the game by an expected margin of 10.5 points. The trojans haven’t won at notre dame or oregon since 2011.
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